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KPTI
Volume: 118.43K
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Karyopharm Therapeutics (KPTI) Stock Forecast & Price Target

Karyopharm Therapeutics (KPTI) Analyst Ratings

Based on 5 analyst ratings
Buy
Strong Buy 20%
Buy 80%
Hold 0%
Sell 0%
Strong Sell 0%

Bulls say

Karyopharm Therapeutics Inc is experiencing a favorable outlook driven by the increasing valuation of its drug XPOVIO for multiple myeloma (r/rMM), now estimated to yield $130 million by 2026, reflecting steady demand in community settings which accounts for 60% of revenue. Additionally, the company has raised the valuation for selinexor in the context of TP53 wild-type endometrial cancer to $73 million, indicating a robust potential market as they apply a favorable revenue multiple. The strategic expansion of indications for XPOVIO, along with projected sales growth to approximately $500 million, underscores the company’s potential for sustained revenue generation and market presence.

Bears say

Karyopharm Therapeutics Inc faces multiple hurdles that contribute to a negative outlook on its stock. Key risks include disappointing clinical data, delays in clinical development timelines, potential failures in obtaining regulatory approvals for its lead product, XPOVIO, and constraints in achieving commercial success due to an increasingly competitive landscape. With recent R&D expenditures coming in below expectations and concerns over a narrow therapeutic window for XPOVIO, the company could face significant valuation challenges, particularly if setbacks occur in its clinical programs or market uptake remains limited.

Karyopharm Therapeutics (KPTI) has been analyzed by 5 analysts, with a consensus rating of Buy. 20% of analysts recommend a Strong Buy, 80% recommend Buy, 0% suggest Holding, 0% advise Selling, and 0% predict a Strong Sell.

This aggregate rating is based on analysts' research of Karyopharm Therapeutics and is not a guaranteed prediction by Public.com or investment advice.

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FAQs About Karyopharm Therapeutics (KPTI) Forecast

Analysts have given Karyopharm Therapeutics (KPTI) a Buy based on their latest research and market trends.

According to 5 analysts, Karyopharm Therapeutics (KPTI) has a Buy consensus rating as of Nov 26, 2025. This rating is provided by third-party analysts and is not investment advice from Public.com.

Wall Street analysts have set a price target of $15.40, reflecting a 0.00% increase from the current stock price.

Financial analysts have set a price target of $15.40, indicating a 0.00% increase from the current stock price, but ratings and forecasts are frequently updated based on market conditions, earnings reports, and industry trends. This prediction is provided by third-party analysts and is not investment advice from Public.com.

Karyopharm Therapeutics (KPTI)

Volume: 118.43K

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