
PLRX Stock Forecast & Price Target
PLRX Analyst Ratings
Bulls say
Pliant Therapeutics Inc. is positioned positively due to its focus on a localized strategy for fibrosis treatment, notably through the dual blockade of integrins αvβ8 and αvβ1, which is expected to enhance immune activation while minimizing systemic side effects. The company's primary product candidate, bexotegrast (PLN-74809), has already shown signs of efficacy in idiopathic pulmonary fibrosis (IPF) trials, indicating potential for future development, including plans for a new dose-ranging Phase 2b study. Additionally, the favorable risk-benefit profile of bexotegrast in primary sclerosing cholangitis (PSC) signals a broader opportunity for the drug, further enhancing the positive outlook for Pliant Therapeutics's stock valuation.
Bears say
Pliant Therapeutics has faced significant challenges following the discontinuation of its BEACON-IPF Phase 2b trial due to a safety-related imbalance, primarily characterized by an unexpectedly low rate of adverse events in the placebo group. Financial performance also reflects ongoing struggles, with a reported net loss of $49.7 million for the fourth quarter of 2024, indicating substantial operational costs without progress in product development. Furthermore, the company’s pipeline appears limited, as the discontinuation of the IPF program leaves a considerable void in their drug development efforts and signals a lack of near-term upside potential.
This aggregate rating is based on analysts' research of Pliant Therapeutics and is not a guaranteed prediction by Public.com or investment advice.
PLRX Analyst Forecast & Price Prediction
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